A new study led by Dr. Peter Canoll’s lab, in collaboration with researchers at Columbia University Irving Medical Center, Zuckerman Institute, and Irving Institute for Cancer Dynamics, along with ...

Theranib Inc. has divulged retinal dehydrogenase 1 (ALDH1A1; RALDH1) and/or retinal dehydrogenase 2 (ALDH1A2; RALDH2) and/or aldehyde dehydrogenase family 1 member A3 (ALDH1A3; RALDH3) inhibitors ...

Pediatric low-grade gliomas (pLGGs) are a group of tumors that affect children, teenagers, and young adults. They are the most common tumors of the brain and spinal cord in young people.

A group led by the Department of Neurosurgery, Brain Research Institute, Niigata University, has succeeded in the diagnosis of leptomeningeal disease in diffuse midline gliomas by detecting H3K27M ...

Gliomas account for almost 80% of primary malignant brain tumors, and they result in more years of life lost than do any other tumors. Glioblastoma, the most common type of glioma, is associated ...

Aldehyde dehydrogenases 1 family member A1(ALDH1A1) gene codes a cytoplasmic enzyme and shows vital physiological and pathophysiological functions in many areas. ALDH1A1 plays important roles in ...

including pathological glioma grade and IDH status, was first investigated. Analysis of the TCGA dataset showed higher expression levels of ALDH16A1, ALDH3B1, ALDH7A1, ALDH1A2, ALDH3A1 and ALDH1A3 in ...

They grow rapidly and can spread to areas near the original tumor and to other areas in the brain. Astrocytomas are the most common type of glioma, accounting for about half of all childhood brain ...