This valuable work provides novel insights into the substrate binding mechanism of a tripartite ATP-independent periplasmic (TRAP) transporter, which may be helpful for the development of specific ...

and using main chain rather than side chain interactions minimizes the likelihood of point mutations affecting the binding.” The manuscript by Goyal et al report substrate-bound and substrate-free ...

近期在人类和小鼠细胞中的研究已发现ATP结合盒（ABC）C亚家族成员1（ABCC1）是一个直接的ATP依赖性cGAMP外排泵。这些研究还表明，细胞内源性的STING ...

Zhejiang Province Key Laboratory of Quantum Technology and Device, School of Physics, Zhejiang University, Yuhangtang Road 866, Hangzhou 310058, China ...

These structures allow us to map out the conformational transitions associated with ligand and nucleotide binding and visualize key differences in how substrates and inhibitors interact with the TMD.

A new research paper was published in Volume 16, Issue 22  of Aging (Aging-US) on December 20, 2024, titled, “Impaired renal ...

ft. distribution facility for its walk-in units in Temple. British maker of solar- and battery-powered transport refrigeration units expands production at its Leatherhead, Surrey, headquarters ...

These tournaments attract the best players in the world and are considered the most prestigious events in tennis. In addition to the Grand Slam tournaments, the ATP Tour and WTA Tour organize ...

Inflammasomes play a crucial role in innate immunity by serving as signaling platforms which deal with a plethora of pathogenic products and cellular products associated with stress and damage. By far ...

vumc.nl Methods We studied the association between anxiety symptoms, measured with an affective subscale of the Beck Anxiety Inventory, and (extra)striatal 123 I-FP-CIT binding in 127 non-demented ...

See schedule and winners of all ATP Tour, ATP 1000 Masters events and Grand Slams in 2025; more than 4,000 tennis matches and 80 tournaments shown live on Sky Sports; Carlos Alcaraz will defend ...