The actin cytoskeleton is composed of dynamic filament networks that build adaptable local architectures to sustain nearly all cellular activities in response to a myriad of stimuli. Although the ...

In his book The Mathematical Universe, mathematician William Dunham wrote of John Venn’s namesake legacy, the Venn diagram, “No one in the long history of mathematics ever became better known ...

We recommend using your OS's package manager directly instead for improved security but the install script is by no means insecure. In addition to being a runnable CLI tool, D2 can also be used to ...

Excalidraw is an innovative online whiteboarding tool that uses the power of artificial intelligence (AI) to convert simple text prompts into detailed, professional-quality diagrams. Whether you ...

Reduction of ATP levels by drug treatment also affects protrusion formation as well as actomyosin dynamics. Importantly, we find that RhoA/ROCK signaling, which is essential for actin and myosin ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Increased ATP production might contribute to the suppression of osteoclastogenesis through accelerated actin dynamics, which destroys the proper F-actin aggregation during osteoclast differentiation ...

Mechanistically, IL-1β activates RhoA/ROCK signaling through a non-canonical IL-1 receptor-dependent pathway, which drives the enrichment of actin bundles at the cell-cell junctions, thus prevents ...