The Ras–MAPK (mitogen-activated protein kinase) pathway is another important cell-proliferation pathway downstream of EGFR that is frequently activated in cancer. Although mutations in Ras ...
2024 年,非小细胞肺癌(NSCLC)治疗领域迎来了累累硕果。尤其是针对 EGFR 突变 III 期不可切除 NSCLC 的靶向巩固治疗研究,取得了令人振奋的突破性 ...
肺癌的主要亚型非小细胞肺腺癌有比较大的概率可以靶向治疗,对于亚裔的非小细胞肺腺癌患者来说,EGFR基因突变概率非常高,可以达到50%的突变 ...
Janux Therapeutics, Inc. (Nasdaq: JANX) (Janux), a clinical-stage biopharmaceutical company developing a broad pipeline of novel immunotherapies by applying its proprietary technology to its Tumor ...
- Encouraging progress supports near-term focus on lead wholly-owned program, CX-2051 (EpCAM PROBODY® ADC). Initial Phase 1a clinical data in advanced metastatic colorectal cancer (CRC) are ...