Aug. 21, 2024 — An international team of scientists has uncovered a mechanism by which acute myeloid leukemia (AML) cells sustain their growth. AML cells prevent the synthesis of proteins that ...

The CD34+CD38− cells, isolated from acute myeloid leukemia (AML), were shown to be enriched leukemic stem cells (LSC). We isolated the CD34+CD38− cell fraction from AML and compared their gene ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

Acquired miR-142 deficit in leukemic stem cells has been associated with chronic myeloid leukemia blast crisis. Here the authors show that acquired miR-142 deficit in T cells further enables ...

Acute colonic ileus or Ogilvie's syndrome is an acute nonmechanical colonic obstruction with an unclear pathophysiology. This motility disorder generally occurs in elderly patients with serious ...

Acute colonic ileus is an uncommon motility disorder of unclear pathogenesis that predominantly occurs in older patients with severe medical or surgical disease. Conservative management is the ...

2012). It was shown in the same study that T cells are required for the rejection of inoculated tumor cells. The authors concluded that OGR1expression in myeloid-derived cells is needed for the ...

In the past few decades, considerable progress has been made in understanding the complex interaction of host and pathogen, and the pathophysiology underlying both meningococcal septicaemia ...

Aston Martin Lagonda Global Holdings Plc designs, creates, and exports cars. Its sports cars are manufactured in Gaydon with its luxury DBX SUV range manufactured in St. Athan, Wales. The company ...