A critical factor in this devastating disease is the metabolic reprogramming exhibited by cancer cells, particularly the preference for aerobic glycolysis over oxidative phosphorylation ...

Then, the role of aerobic glycolysis in IL-1β production was evaluated, as well in vitro as in vivo using 18 F-fluorodeoxyglucose positron emission tomography imaging and glucose uptake assay, and ...

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been ...

Metabolic alterations in cancer cells are numerous and include aerobic glycolysis, reduced oxidative phosphorylation and the increased generation of biosynthetic intermediates needed for cell ...

Regular aerobic exercise could significantly reduce disease markers associated with Alzheimer’s, new research led by scientists at the University of Bristol (UK) and the Federal University of ...

1 Children's Health and Exercise Research Centre, University of Exeter, Exeter, UK 2 Health and Use of Time Group, Sanson Institute for Health Research, University of South Australia, Adelaide, ...

Aerobic respiration requires the mitochondria of the cell and occurs over three distinct stages; glycolysis, the Krebs cycle and the electron transport chain. The rate of aerobic respiration is ...

Mechanistically, FBXW7 binds to S6K1 and promotes its ubiquitination and proteasomal degradation, which in turn impacts glycolysis and brown preadipocyte proliferation via lactate. Besides, the ...

2022). Yang et al. discovered that exosomal miRNA-146a-5p, produced by aged HCC cells, can inhibit HCC cell proliferation by suppressing aerobic glycolysis and promote HCC cell senescence by ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...