For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

Chemical Engineering is concerned with the design and operation of processes which convert materials and energy into the higher value products we use every day. It understands the processes which ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

which has thus become one of the most important means we have for investigating molecular structure. There is, indeed, no experimental method that gives more detailed information on this subject.

The first step in USNCO, held each March. High school students can participate by registering with ACS. Registration does not guarantee participation. Students will be notified by their ACS Local ...

This study investigates the potential clinical synergy between the PARP inhibitor niraparib (Zejula) and concomitant statins, exploring their combined effects on progression-free survival (PFS) in ...

Beginning in the late 1970s, he effectively became a master builder in the nano universe — seeking how to use molecular bonds to fashion biological structures designed with a special purpose.

These shifts highlight specific molecular mechanisms ... such as immune signaling and neuronal structure maintenance. These analyses uncovered significant losses in neurogenic potential and ...

Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China ...

The test results prove that the PMFF predicts the molecular structure more reliably and interprets the biological phenomena extremely accurately. It is therefore suitable for describing biological ...

Through structure-guided evolution, a mutant form of UGT94D1 with significantly enhanced catalytic activity was created; this mutant, UGT94D1-F119I/D188P exhibited a 6.33-fold improvement in catalytic ...