The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Nephrotoxicity, the major complication of long-term therapy with amphotericin B, is attributed to drug-induced renal vasoconstriction plus a direct toxic action on renal tubules. Hypokalemia and ...

Intravenous amphotericin B should be reserved for those with severe disease. Oral triazole antifungals have had a great impact on the management of coccidioidomycosis. Both fluconazole and ...

This structure allows them to encapsulate both hydrophilic drugs (in the aqueous core ... 3,5 Liposomes are also used in antifungal therapies, such as Ambisome®, to deliver amphotericin B with reduced ...

For Cresemba, this comprises a milestone payment for sales in Canada, by AVIR Pharma Inc, as well as the first sales milestone payment for the Middle East and North Africa (MENA) region, by Hikma ...

The company has one clinical-stage candidate in SF001, an analogue of the well-established antifungal amphotericin B that Elion describes ... with a “novel chemical structure and binding mode.” ...

Three ways were proposed to explain the resistance mechanism: (1) the corresponding amino acids docked with azoles are changed, (2) the structure of the binding cavity is rearranged, leading to ...

and the structure, shape and size of zygospores (sexual stage) including suspensory cells. Fungal identification guides provide sufficient identification keys and subsequently information on the ...

Molson Coors Beverage Co. Cl A-7.50% $11.29B Molson Coors Beverage Co. Cl B-2.48% $11.29B ...

The unique properties of electrospun fibrous membranes, such as large surface area, compositional versatility, and customizable porous structure, make them ideal for advanced biomedical applications ...

and rigors associated with anesthesia or drug therapy (typically chemotherapy or amphotericin B). Interventions were made for all patients receiving meperidine for pain management. Almost all ...

Cluster B disorders are taxonomically grouped together by the DSM-V because a single, clear-cut diagnosis is very rare, and patients often exhibit a number of overlapping symptoms. For example ...