Breast cancer (BC) is one of the most common malignancies and the leading cause of cancer-related mortality in women. Androgen receptor (AR) is frequently expressed in diverse BC subtypes.

Second, we present evidence that androgen receptors (AR) and other steroid receptors are expressed in the mesocorticolimbic ... Fifth, we describe how androgens modulate the neurochemistry and ...

It was not until later that it was discovered that androgen insensitivity was caused by mutations in the androgen receptor gene. The symptoms of androgen insensitivity depend on the type. Individuals ...

School of Environment, Hangzhou Institute for Advanced Study, University of the Chinese Academy of Sciences, Hangzhou, Zhejiang 310024, China College of Life Science, China Jiliang University, ...

We have discovered two types of 5′ intronic gene mutation that impair androgen receptor (AR) mRNA expression severely, and cause complete androgen insensitivity. Labium majus skin fibroblasts ...

Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The ...

But of course, the last few years, really the last decade to decade and a half, has been the advent of what we call, now call ARPIs, or androgen receptor pathway inhibitors. And these are really ...

2. Clarity Pharmaceuticals. Clarity receives U.S. FDA Fast Track Designation for 64Cu-SAR-bisPSMA in biochemical recurrence of prostate cancer. https://www.claritypharmaceuticals.com/news/ftd-2/ ...

Adrenal insufficiency or bilateral oophorectomy (surgical menopause) result in severe androgen deficiency, which can be clinically associated with impaired libido, drive and energy. Physiological ...

is an androgen receptor inhibitor (ARi) with a distinct chemical structure that competitively inhibits androgen binding, AR nuclear translocation, and AR-mediated transcription. Warnings & Precautions ...

1月30日，山东大学基础医学院孙金鹏教授团队，联合德国莱比锡大学Ines Liebscher教授团队，山东大学易凡教授团队、肖鹏教授团队和于晓教授团队，在《细胞》（Cell）在线发表了研究论文“Identification, structure and agonist design of an androgen membrane ...