Purpose. Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...

Endo's slide into bankruptcy follows in the footsteps of Purdue Pharma – which filed in 2019 but is still negotiating opioid settlement and corporate restructuring terms – as well as ...

The Sacklers will no longer have liability protection from future lawsuits. The company and the once-prominent family behind the drug OxyContin agreed Thursday to increase their financial ...

A118G (43AA, 19AG, 18GG) 80 Taiwan females following abdominal hysterectomy GG had significantly higher postoperative day 1 morphine requirements [104] A118G Caucasians: 66 = AA, 29AG; Africans: 1 ...

An opioid overdose occurs when opioids have fully blocked the brain's opioid receptors, causing a person's breathing to slow down and ultimately stop. Naloxone works by knocking the opioids out of ...

For people who study the opioid epidemic, 2025 marks a grim anniversary: It has been 30 years since the Food and Drug Administration approved the opioid OxyContin for the treatment of chronic pain.

Purdue Pharma and its Sackler family owners have reached a new $7.4 billion settlement to resolve thousands of lawsuits alleging that the pain medication OxyContin caused a widespread opioid ...

Purdue Pharma and its Sackler family owners have reached a new $7.4 billion settlement to resolve thousands of lawsuits alleging that the pain medication Oxycontin caused a widespread opioid ...

The $7.4 billion deal with the OxyContin maker creates a controversial legal-defense fund for the Sacklers. Massachusetts residents who lost relatives to opioid overdoses expressed elation ...

If you use drugs, do not use alone. Call 911 if you suspect an overdose. Naloxone can temporarily reverse an opioid overdose if it is given right away. Kits are free at sites across Alberta. Canada's ...

Each game in the series offers unique and awe-inspiring summon animations. Players can control powerful summons to unleash devastating attacks on foes. Final Fantasy is one of the most popular ...