Glutamate uptake is mainly accomplished by astrocytes which either convert glutamate to glutamine or feed it into their own metabolism. Normally, the astrocytic glutamate transporters are indirectly ...

Discoveries of glutamate and glutamine pools within intercellular compartments led to suggestions of the glutamate–glutamine cycle working between neurons and astrocytes. The glutamate/GABA–glutamine ...

Some examples of mouse models in which astrocyte protein function is altered are detailed in Table 1. In addition to cellular hypertrophy and upregulation of specific genes associated with ...

indicates that mutant huntingtin is also present in the nuclei of astrocytes, a phenomenon that becomes more robust with age and corresponds with a downregulation of glutamate transporters in ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

only affecting the ability of astrocytes to return to their original volume after OGD. In addition, we have shown that knockout of AQP4 or TRPV4 can cause expression changes of other proteins, ...

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China University of Chinese Academy of ...

Astrocytes from both groups had deficits in glutamate signaling. The cool part is what happened next: When they exposed astrocytes to clozapine, glutamate signaling normalized—but only in the ...

of Physiology & Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, United States (A) Shv expression in glia maintains ambient glutamate concentration at the NMJ.

6 Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia Correspondence to Associate Professor Steve Vucic, Sydney Medical School Westmead, University of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During mitosis, the condensin I and II ...