Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

ER stress can contribute to autophagy via activation of JNK, XBP1, CHOP, and ATF4. Red dash arrows indicate the final outcome of the activated pathways, such as apoptosis and autophagy, caused by ...

Dr. Weickert will present Pacylex at the OBIO® Investment Summit and Early Technology Showcase February 5-7, 2025, at the Arcadian Court & Loft, Toronto Mr. Kamdar will present Pacylex at the PWMC ...

The 80-patient placebo-controlled randomized Phase 2 study will evaluate the efficacy of opaganib in combination with Bayer's darolutamide in men with metastatic castrate-resistant prostate cancer ...

Beside developmental abnormalities, it may lead to tumorigenesis, autoimmunity, and other serious health problems. Deregulated apoptosis may also be the leading cause of cancer therapy chemoresistance ...

The 80-patient placebo-controlled randomized Phase 2 study will evaluate the efficacy of opaganib in combination with Bayer's darolutamide in men with metastatic castrate-resistant ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...

Apoptosis is a mechanism of programmed cell death and is essential for development and homeostasis. Cell stress stimulates pro-apoptotic signalling pathways that activate caspase proteases and ...

We can confirm the starting line-ups and substitutes for this evening’s Barclays Women’s Super League clash with Manchester United at Tottenham Hotspur Stadium (6.45pm UK). Robert Vilahamn has made ...

Robert Vilahamn spoke to the media at Hotspur Way on Friday afternoon, ahead of our Barclays Women’s Super League clash against Manchester United at Tottenham Hotspur Stadium on Sunday (6.45pm UK).

Arsenal delivered a statement of intent in the Premier League title race with a 5-1 hammering of champions Manchester City to close the gap at the top to six points on Sunday. Captain Martin ...