This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

This review explores the potential of CAR-T cell therapy in CRC by analyzing clinical trials and highlighting prominent CRC-specific targets. We discuss the challenges such as immunosuppressive ...

The findings could point to new strategies for managing disorders such as diabetes, obesity and cancer ... here is that we’re seeing mass migration of immune cells between the intestine ...

to target a cell-surface receptor called DR5 (death receptor 5) that many tumor cells have. When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis.

iPSC-derived cell therapies have the potential to transform cancer care by offering scalable, 'off-the-shelf' treatment options. However, bringing efficacious therapies to patients requires robust ...

Scientists have struggled for decades to understand why radiation therapy kills cells from the same tumor in different ways. This is important because some forms of cell death are unnoticed by the ...

Collaboration leverages Ginkgo's cell engineering and screening platform to enhance the potency and persistence of Universal Cells' iPSC-derived immune cell therapeutics BOSTON, Jan. 13, 2025 ...

State Key Laboratory of Analytical Chemistry for Life Science, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Road ...

Moshe Sade-Feldman, PhD (also a KF-CCR PI and Asst. Prof. of Medicine) and his team were instrumental in performing the needed single-cell RNA sequencing studies to determine how the tumor ...