C&EN22 天
From Pseudocyclic to Macrocyclic Ionophores: Strategies toward the Synthesis of Cyclic ...
Department of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61−614 Poznań, Poland ...
C&EN24 天
Deciphering the δ-Lactam Formation and lron-Reducing Activity of Spinactins from ...
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China ...
Frontiers28 天
Deletion of Lytic Transglycosylases Increases Beta-Lactam Resistance in Shewanella oneidensis
Beta-lactam antibiotics are the most widely used group of antibiotics, they target the penicillin-binding proteins (PBPs), eventually disrupting the peptidoglycan synthesis. To combat these ...
Nature11 个月
The exploration of macrocycles for drug discovery — an underexploited structural class
A macrocycle provides diverse functionality and stereochemical complexity in a conformationally pre-organized ring structure ... compound amphotericin B (9) 37, and related derivatives, in ...
Investopedia1 年
How to Analyze a Company's Capital Structure
Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...