for example, owing to dysfunction of the breast cancer type 1 susceptibility protein (BRCA1). Indeed, mutations in BRCA1 are known to predispose individuals to hereditary breast and ovarian cancers.

Several studies have been completed looking at the effect of BPO in women at high risk of developing ovarian cancer because of family history or because of being mutation carriers of either BRCA1 ...

Genetics significantly impact cancer risk, particularly in inherited mutations like BRCA1/BRCA2, which increase ...

and it's known that it takes multiple mutations to form a cancer. However, in some women carrying high-risk genetic variants of BRCA1 and BRCA2, the researchers observed a few "extreme" examples ...

Ethnicity can play a role in the odds of a person having these changes to the gene – for example people ... “Knowing that you’re BRCA1 positive, that you have a mutation that you may have ...