BH3 mimetics are small molecules that mimic BH3-only proteins by binding to and inhibiting the prosurvival members of the Bcl-2 family ... (the majority with follicular lymphoma) received ...

David Hockenbery (Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis): "Bcl-2 is the oncogene located at the breakpoint of the chromosomal translocation t(14;18) ...

Medically reviewed by Doru Paul, MD Immunohistochemistry (IHC) is a special test used by pathologists to detect specific ...

Ann LaCasce, MD, MMSc, director of the Dana-Farber/Massachusetts General Brigham Fellowship in Hematology/Oncology, highlights the role of bispecific antibodies in lymphoma research.

The new use is the third for Kymriah (tisagenlecleucel) in the EU and offers patients with grade 1, 2 and 3A follicular lymphoma that has returned after two or more prior treatments a new ...

Those that grow and spread slowly are described as ‘indolent’, one of the most common types of which is follicular lymphoma ... resistant to chemotherapy 2. Chronic lymphocytic leukaemia ...

Ann LaCasce, MD, MMSc, delved into some of the most recent advances in the lymphoma space, exploring how these new therapies ...

5 “PET-CT to evaluate response to treatment in patients with follicular lymphoma has been increasingly used by clinicians in the last 2 to 3 years, and clinical trials designed since these data ...

Bristol Myers (BMY) announced the Committee for Medicinal Products for Human Use, or CHMP, of the European Medicines Agency, or EMA, has ...