Beta-lactam antibiotics are the most widely used class of drugs for the treatment of bacterial infections. They include penicillin and its derivatives, such as methicillin and amoxicillin, as well as ...

An international team led by Professor Jim Spencer (School of Cellular and Molecular Medicine) have applied a combination of microbiological, biochemical, structural biological and computational ...

It is a first-generation cephalosporin antibiotic, meaning that it was among the first cephalosporins developed. It is also ...

Beta-lactamase inhibitors are designed to overcome a key resistance mechanism that allows pathogens to protect themselves from beta-lactams, one of the most commonly-used antibiotic classes.

Pfizer’s Emblaveo has been approved in the EU with a first-in-class indication in multidrug-resistant (MDR) infections. The drug – a combination of beta-lactam antibiotic aztreonam with beta ...

The drug combination involves cefepime, a widely used beta-lactam (BL) antibiotic with over two decades of proven safety and effectiveness against susceptible gram-negative and gram-positive ...