Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...
The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...
Analytical biochemistry is the study of biochemical ... changes in LC-MS status in large-scale quantitative proteomics experiments. They further prioritized 15 QC metrics and developed an AI ...
Physicists are putting the finishing touches on the Jiangmen Underground Neutrino Observatory, or JUNO, which will delve into the secretive ways of neutrinos, a family of extremely lightweight ...
Scientists at the institution showed through an innovative quantum experiment that light appears to emerge from a material before entering, overturning several decades of prevailing ideas about ...
In this Review, we first discuss the biochemistry and pathophysiology of peroxynitrite and then focus on pharmacological strategies to attenuate the toxic effects of peroxynitrite. These include ...