EMT 的一个标志性特征是上皮细胞完整性丢失，这是由维持上皮细胞间接触的黏附蛋白（如E-cadherin ）降解造成的[56-57] 。这种降解的一个主要驱动因素是基质金属蛋白酶（matrix metalloproteinase ，MMP ）进行蛋白水解消化，因此，MMP 家族蛋白与EMT 过程联系非常紧密[58 ...

Wall Street is off to a volatile start in 2025, with investors stepping on the sell pedal after last week's jobs data, followed by a sharp about-face in sentiment following Wednesday's consumer ...

Moderna's mRNA technology gained rapid validation as sales of its covid vaccine soared in 2021 and 2022, but we think the firm has yet to secure a narrow economic moat around its business ...

Melis­sa Moore helped ush­er in the first mR­NA med­i­cines, but the for­mer Mod­er­na ex­ec­u­tive thinks there’s still a lot of room for im­prove­ment.

But scientists at Moderna are in the late stages of testing what could be the first such shot, using mRNA technology against the virus. Here’s what to know about norovirus and where things stand ...

先前的研究策略大多通过多肽模拟再感染事件来实现局部癌症免疫治疗，但其疗效通常受到多肽表位长度的限制。随着mRNA技术在新冠疫苗研发中取得突破性进展，基于mRNA的疗法展现出靶点丰富、安全性高、研发周期短等优势。因此，利用mRNA技术重启机体的免疫 ...

2024年10月8日，杜克大学Nicholas S Heaton携手mRNA诺奖得主Drew Weissman在《Nature Communications》杂志上发表题为“Improved influenza vaccine responses after expression of ...