Lipid nephrotoxicity could damage the structure and function of the glomerulus and tubules. Figure 2 Differentiation of Treg cells in vivo. TTreg cell development is initiated by TCR signal ...

Pharmacologic or genetic inhibition of PGAM inhibited Treg differentiation and shifted CD4 T cells toward a pro-inflammatory, Th17-like state. Mechanistically, we found that PGAM regulates Treg ...

编辑丨王多鱼排版丨水成文抗 PD-1 联合仑伐替尼（lenvatinib，一种多靶点受体酪氨酸激酶抑制剂）治疗在多种肿瘤中均显示出临床疗效，但潜在的免疫学机制尚不清楚。2025 年 1 月 30 ...

The decrease in CD4 cells during HIV infection seems to be ... and higher LPS levels were associated with greater activation of CD8 + lymphocytes. CD8 + activation also was found to be higher ...

1 contribute to evasion of CD8 + T cell responses. Mutations occurring in T cell epitope hotspots in the viral spike protein and in a highly conserved site in the viral nucleocapsid suggest that T ...

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

CD8 + T cell exhaustion is defined by a unique ... resulting in efficient tumour cell killing in vitro and in a mouse model. Dysregulated CD4 T cells have been implicated in autoimmune liver ...

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell ...

WASHINGTON, Jan 30 (Reuters) - The U.S. Treasury Department said on Thursday it was withdrawing from a global body of central banks and regulators devoted to exploring ways to police climate risk ...

Nasdaq Dividend History provides straightforward stock’s historical dividends data. Dividend payout record can be used to gauge the company's long-term performance when analyzing individual stocks.