COUR Pharmaceuticals, a clinical-stage biotechnology company developing first-in-class, disease-modifying therapies designed ...

A study revealed that probiotics combined with chemotherapy and immune checkpoint inhibitors improve survival, gut health, ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

鳞状细胞癌与基底细胞癌均来自于角质形成细胞的癌变，黑色素瘤来源于黑色素细胞癌变，因此在第一部分内容分析BCC，SCC,黑色素瘤细胞生态图谱后，研究团队将目光聚焦于角质形成细胞以及黑色素细胞。健康角质形成细胞和肿瘤角质形成细胞的二级聚类导致明显分离的健 ...

然而，在哺乳动物物种之间，端粒酶的调控和端粒长度存在显著差异。在人类中，端粒酶的表达局限于少数器官，如睾丸、卵巢和胸腺，许多老化组织中的端粒会逐渐耗尽。但对 60 多种哺乳动物的比较研究发现，包括小鼠在内的许多生物并没有端粒介导的复制性衰老现象。小鼠的端粒酶表达限制较少，大多数组织都能表达较高水平的 Tert mRNA 和端粒酶活性。实验室内的近交系小鼠，如 ...

Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...

CD4-cell counts and T-cell activation levels were ... and higher LPS levels were associated with greater activation of CD8 + lymphocytes. CD8 + activation also was found to be higher in elite ...

编辑丨王多鱼排版丨水成文抗 PD-1 联合仑伐替尼（lenvatinib，一种多靶点受体酪氨酸激酶抑制剂）治疗在多种肿瘤中均显示出临床疗效，但潜在的免疫学机制尚不清楚。2025 年 1 月 30 ...

Priya Hays, Hays Documentation Specialists, discusses innovations and advancements in the development of personalized cancer ...

在格拉斯哥举行的HIV药物治疗会议上，一份病例报告显示， 一名接受具有罕见突变（该突变可阻止病毒进入细胞）的供体干细胞移植以治疗癌症的患者，可能成为 第八例长期病毒缓解的HIV感染者。

点击蓝字关注我们神经性疼痛作为最顽固的慢性疼痛类型，在女性中的患病率显著高于男性。性别依赖的神经免疫机制是神经损伤引起的异常性疼痛的基础。动物实验表明小胶质细胞介导雄性慢性疼痛的发生过程，而适应性免疫系统介导雌性疼痛反应。Panx ...

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...