Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication 1. These findings ...

“Furthermore, DR5-scFv sEVs significantly inhibited MDSCs and cancer-associated fibroblasts (CAFs) in the TME and activated CD8+ T cells in organotypic patient-derived melanoma slice culture ...

Cancer cells divide more rapidly than normal cells, so most cancer treatments focus on killing these fast-dividing cells. However, this often leads to side effects since normal cells can also be ...

When reduced to about one-thousandth the width of human hair, gold nanoparticles shine as therapeutic agents for cancer therapy. For instance, specks of the precious metal are used in photothermal ...

in which exogenous SYT-SSX fusion neoantigen was loaded into stimuli-responsive nanoparticles (NPs) formed by mPEG-PVGLIG-PCL copolymers (Neo-AgNPs) for tumor targeting delivery. In situ, this ...

The ability to transform cancer cells back into normal cells represents a monumental leap in cancer treatment. With fewer side effects and a reduced risk of recurrence, this technology promises a ...

16, 2025 — Two new studies have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials ... Jan. 3, 2025 — Tumor cells ...

Scientists found that healthy women can carry genetic changes in their breast cells that are thought to be characteristic of invasive breast cancer. Most cancer cells have too many or too few ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other ... functional states of CD8+ CAR T cells during ...

The use of oncolytic viruses (OVs) to induce immunogenic cell death (ICD) in tumor cells is a well-established strategy for initiating the cancer immunity cycle (CIC). This process promotes the ...