IL-1 signaling in DCs promotes their ability to induce T cell activation, but also direct action of IL-1 on both CD4 + and CD8 + T cells, either alone or in synergy with prototypical polarizing ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

CD8 + T cell exhaustion is defined by a unique transcriptional ... IL-10 is dispensable for their suppressive function. Vaccination in glioblastomas does lead to the emergence of tumour-antigen ...

Lipid nephrotoxicity could damage the structure and function of the glomerulus and tubules. Figure 2 Differentiation of Treg cells in vivo. TTreg cell development is initiated by TCR signal ...

Collaboration to explore the immunoregulation of NK and T cells within the tumor microenvironment (TME) by CAPTN-3, with the ...

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, ...

which is enhanced by interferon-γ released by activated T cells. MSCs also impair B-cell functions, such as antibody production. After in vivo intravenous administration, MSCs can induce T-cell ...

The Phase 1b/2a study will assess the safety of CNP-103 in adults (aged 18-35) and pediatrics (aged 12-17) who have Stage III or newly diagnosed (within the last 6 months) T1D as well as C-peptide ...

Priya Hays, Hays Documentation Specialists, discusses innovations and advancements in the development of personalized cancer ...

where its frontline defenders -- T cells -- lose their ability to function effectively. ... First Mouse With Two Male Parents to Reach Adulthood Jan. 28, 2025 — A team of stem cell scientists ...

Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...

Modular Photoswitchable Molecular Glues for Chemo‐Optogenetic Control of Protein Function in Living Cells. Angewandte Chemie International Edition , 2025; DOI: 10.1002/anie.202416456 ...