CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

563794) containing conjugated antibodies (1:100) for the t cell-surface markers CD45, CD8, LFA-1, CXCR6, CXCR3 and CD69. After staining and fixation, cells were stored at 4°C until flowcytometric ...

Bryostatin-1 directly reduces exhausted-associate markers and improves proliferative capacity ... containing 2.5 mM CaCl 2. For surface staining of single or repeat peptide stimulated murine CD8+ T ...

T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for ...

1Department of Immunology, Center for Systems Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. 2School of Medicine, Tsinghua University, Beijing, China.

T-cell lymphoma is a type of lymphatic cancer that starts in the T lymphocytes (T cells), a type of white blood cell. T lymphocytes (T cells) and B lymphocytes (B cells) are two types of white blood ...

DeGolier et al, Antigen experience history directs distinct functional states of CD8+ CAR T cells during the antileukemia response, Nature Immunology (2025). DOI: 10.1038/s41590-024-02034-1 ...

Jan. 23, 2025 — Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some ...