Chronic rhinosinusitis (CRS) including nasal polyps is a chronic inflammatory disease involving the mucosa of the nose and one or more paranasal sinuses. Despite differing hypotheses, the cause ...

It is often categorized into two main types: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps. Recent research has focused on understanding the mechanisms behind CRS, its epidemiology ...

Exposure to irritants has been shown to increase nasal symptoms and cause exacerbations ... an important first step in treating all forms of CRS. The EP3OS guidelines evaluate the severity ...

ECP contributes to the formation of nasal polyps and the chronic progression of CRS through diverse mechanisms, involving disruption of epithelial cells, stimulation of fibrosis, and aggravation of ...

AstraZeneca has failed in its bid to get US approval for its IL-5 inhibitor Fasenra as a treatment for chronic rhinosinusitis in people with nasal polyps, after the FDA rejected its marketing ...

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition characterized by persistent nasal obstruction, discharge, facial pressure, and olfactory dysfunction. CRSwNP ...

The MERIT trial was a randomised, double-blind, placebo-controlled, parallel-group, 52-week phase III study to assess the efficacy and safety of mepolizumab in patients with chronic rhinosinusitis ...

Stuffy, sneezing, miserable: folks plagued by chronic sinusitis know the feeling all too well. Experts at University of Cincinnati Health say it's also an all-too-common affliction, affecting an ...

Adenomatous polyps typically do not cause symptoms unless they progress to colon cancer. Even then, there may be no sign of a problem until the malignancy is advanced. This is why colon cancer ...

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