Two protocols for switching between carvedilol, a third-generation nonselective agent with vasodilation through α 1 blockade, and a β 1-selective agent (e.g., metoprolol, atenolol) are described ...

Maximum plasma concentrations of carvedilol occur 1-2 hours after oral administration. [9] Absolute bioavailability of carvedilol is approximately 23% due to extensive first-pass metabolism.

Discover a study in which non-selective β-blockers have demonstrated significant potential in preventing decompensation.

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