little is known regarding the exact participation of such receptors in the context of immune response in vivo. This paper evaluates a recent work that utilizes one such molecule, the human CD206 ...

Srinivas V. Kaveri, DVM, PhD, Unite 872, Institut National de la Sante et de la Recherche Medicale, F-75006 Paris, France and Centre de Recherche des Cordeliers, Equipe 16 Immunopathologie et ...

M2型肿瘤相关巨噬细胞与肿瘤细胞分化程度显著相关, 是乳腺癌、胶质母细胞瘤和胃癌等恶性肿瘤增殖和转移的重要标志物. CD206是M2型巨噬细胞特异性的检测靶点, Teesalu等通过噬菌体展示技术筛选了靶向CD206的多肽CSPGAKVRC (UNO). FAM修饰的UNO与CD206抗体共定位成像小鼠 ...

In preliminary studies, we discovered that selected typical and atypical antipsychotic drugs interacted with virtually every biogenic amine receptor tested, in confirmation of many prior studies ...

DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface marker of interleukin 4 (IL-4)-activated human macrophages [M(IL-4)], which historically represent the ...

Macrophages, which exist in almost all tissues and organs, not only contribute to immune regulation, tissue regeneration and remodeling (1) but also play critical roles in the occurrence and ...

Xiamen Cell Therapy Research Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China ...

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This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...