Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Mitosis will produce two daughter cells which ... Interphase is the longest stage of the cell cycle. DNA replicates to form two copies of each chromosome, ready for cell division.

NPCs are built from nucleoporins (Nups) through a sequential assembly order taking place at two different stages during the cell cycle of mammalian cells: at the end of mitosis and during interphase.

The completion of mitosis is governed by the dephosphorylation ... orders and coordinates the events of the eukaryotic cell-division cycle 1. The central components of this system are the cyclin ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz investigated ...

This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...

Wintering Monarch butterflies (Danaus plexippus), Santa Cruz, California. Masses of migrants gather in eucalyptus groves to overwinter before returning north; their numbers have decreased as a ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

State Key Laboratory for Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China ...