Receptors are generally transmembrane proteins, which bind to signaling molecules outside the cell and subsequently transmit the signal through a sequence of molecular switches to internal ...

Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Varjosalo Lab's longstanding interest is the global and comprehensive understanding of how key cellular signaling molecules; protein kinases, protein phosphatases and transcription factors mediate ...

Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

Nail pathology encompasses a variety of conditions ... Wnt signaling pathway: A complex network of proteins involved in cell signaling that plays a crucial role in cell development and growth.

Further, effective TFEB/V-ATPase signaling is critical for lysosomal homeostasis and immune regulation in the context of Tau/NFT pathology. This will be testing using novel mouse models and ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...