最近的研究发现ECSIT在非免疫细胞和免疫细胞中对肿瘤发生有重要影响。肠道上皮细胞中ECSIT的缺失引起线粒体功能损伤并促进代谢重编程，谷氨酸代谢增加引起α-酮戊二酸/琥珀酸比率升高，进而促进TET去甲基化酶激活并诱导选择性翻译起始因子eIF4A1/ ...

Armed with a deep understanding of the structure of cells, professionals in the field of Cell and Molecular Biology (CMB) are leading the charge against some of the world's most prevalent illnesses ...

The course explores concepts and methods in advanced molecular cell biology and protein biochemistry. Molecular mechanisms responsible for the signalling and biochemical responses of cells will be ...

Specialized training in signal transduction and cellular regulation is provided by formal graduate coursework and original scientific research in this area. The program provides multi-disciplinary ...

Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

Such broad relevance ensures that mechanistic advances will have significant impacts on the field of signaling biology, as well as on the development of new classes of (i) broad-spectrum antibiotics, ...

metabolism and signaling networks. The department is well-equipped for research in modern molecular and cell biology. Facilities include next generation sequencing platforms, cell imaging systems, ...

Research Areas: Cancer Pathobiology & Immunology, Cancer Genomics, Metabolomics, & Epigenetics, Carcinogenesis & Tumor Microenvironment, Metastasis & Experimental Therapeutics, Cancer Cell Biology & ...