In this review, we present an overview of the epigenetic regulation of NK cell-mediated antitumor immunity, including DNA methylation, histone modification, transcription factor changes, and microRNA ...

This review provides an overview of TLR signaling pathways and their regulators and discusses how TLR signaling, directly and indirectly, regulates cell-mediated immunity. In addition, we also discuss ...

Although B cells ... cell-mediated processes that are involved in presenting antigen to B cells in vivo. You have full access to this article via your institution. As cells of the immune system ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Triggering receptor expressed on myeloid cells 2 (TREM ... liver axis and innate immunity play a significant role in liver injury. Impaired intestinal permeability may promote liver inflammation due ...

1 Department of Medicine, Division of Gastroenterology & Hepatology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK 2 Wellcome Trust PhD Programme for Clinicians, Cambridge Institute ...

Autoimmune disorders occur when immune cells go wrong and attack the body’s own tissues. Currently, autoimmune disorders are largely treated by broad immunosuppressive agents and blocking antibodies, ...

CARD9 is a fundamental signalling-molecule in Th17-responses and antifungal immunity; thereby positioning it at a compelling ... which environmental fungi trigger Dectin-1 on neutrophils through a ...

Most importantly, he found differential expression changes that always led to prosurvival adaptation of senescent cells mediated by BCL-XL, an anti-apoptotic protein that prevents the process of ...

Battling a chronic disease is like running a marathon where T cells, the immune system’s frontline defenders, are the runners. When the starter’s pistol fires, the runners are fast and strong.

1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...