Chromatin organization strengthens DNA for mechanically stressful processes like mitosis, helps protect DNA from damage and is important in the control of gene expression and DNA replication.

Although it disappears temporarily in certain stages of mitosis (Naumova et al., 2013) and zygotic genome activation (Du et ... 2017) and the distinction in gene activity between compartments, the ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.

Consequently, mitosis-related defects have been overlooked as therapeutic targets in this disease ... and motility and ultimately tumor growth and invasiveness. Chromatin modifiers such as SETD2 ...

By establishing loops and defining chromatin domains, cells can achieve coordinated control over multi-locus segments of the genome. This is thought to be achieved using scaffold/matrix attachment ...

The following questions could be addressed in a Phd project - How do HPV interact with the cell division machinery for successful nuclear delivery, and how does this, in turn, affect mitosis? - How is ...

The activity on this page has been designed by educational experts to help you to understand the three stages of mitosis. Interact with the activity to see the mitosis phases and descriptions.

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...