Since the 1980s, the average life expectancy of a person with Down’s syndrome has more than doubled ... t been allowed to take part in the clinical trials for Alzheimer’s drugs.

Introduction: Vici Syndrome is a rare, severe, neurodevelopmental/neurodegenerative disorder with multi-systemic manifestations presenting in infancy. It is mainly ...

These results strongly indicate that ongoing, chronic treatment with QRX003 is necessary for a continued positive clinical outcome in Netherton Syndrome patients. Table 1: First Patient Data from ...

by Dr Esther Corker, Dr Claire McCall and Dr Liz Marder ...

After winning a breakthrough therapy designation for its Hunter syndrome enzyme replacement therapy, Denali Therapeutics is ...

Clinical Genetic Service, Department of Health, Hong Kong SAR, China Background: Costello syndrome (CS) is due to mutations in HRAS, with the most common mutation being c.34G>A (p.G12S), found in most ...

covering a clinical spectrum which can extend from relatively mild symptoms (headache, dizziness, myalgia, smell and taste impairment) to serious neurological complications (stroke, venous sinus ...

The occurrence of serum thyroid autoantibodies at the time of clinical diagnosis is shown in fig 2 ... Because symptoms of hypothyroidism might be mistaken for symptoms related to the natural course ...

Standard corticosteroid treatment is, however, of uncertain clinical value in the maternal HELLP syndrome. High-dose treatment and repeated doses should be avoided for fear of long-term adverse ...

Metabolic syndrome affects between 30% and 40% of adults by age 65. It's rare to have metabolic syndrome symptoms—so the diagnosis depends on blood tests and other clinical measures. Lifestyle changes ...

JAAOS: Case Study AAOS Appropriate Use Criteria: Management of Carpal Tunnel AAOS Now: Board Approves Performance Measures for Carpal Tunnel Syndrome, Appropriate Use Criteria for Hip OA ...

“Longer-term clinical ... cell that breaks down materials including GAGs. The current standard of care, enzyme replacement therapy, partially treats physical symptoms but does not cross the ...