Platelets play an important role in atherothrombotic disease. The currently available antiplatelet drugs target key steps of platelet activation including thromboxane A 2 synthesis, ADP-mediated ...

Clinically significant reductions in bleeding underscore abelacimab’s strong potential to address an unmet need for patients ...

Pharmacogenomics. 2014;15(4):509-528.

While the drug works by increasing a calming brain chemical called GABA, it also appears to lower PER2 gene activity during nighttime, leaving the heart more vulnerable to damage. This discovery ...

Additionally, pharmacogenetic factors, such as the CYP2C19 genotype, have been shown to influence the effectiveness of clopidogrel, a common ... Antiplatelet Therapy (DAPT): The use of two ...

Common drugs like ibuprofen and antibiotics may reduce the risk of dementia, a study suggests. Researchers from the universities of Cambridge and Exeter identified several medications - already ...

Common anti-inflammatory drugs such as ibuprofen may cut dementia risk, a major medicines study suggests. Researchers investigated whether existing treatments already used for other ailments could ...

Scientists hope to investigate whether common drugs could be used to help fight dementia after ibuprofen and some prescription antibiotics, antivirals and vaccines were associated with a reduced ...

Clinical practice guidelines on the use of antiplatelet therapy should aim to be more consistent in how they prioritize ischemic and bleeding risks across patient groups, argue the authors of a new ...

Once every four weeks maintenance dosing may be easier for patients and care partners to continue treatment Alzheimer's ...

A commonly-used heart drug derived from the foxglove plant can “dissolve” clusters of breast cancer cells to prevent the disease spreading, a study suggests. Certain tumour types release ...

Over 3500 major leg amputations were performed by vascular surgeons in the UK in 2023 - and many were preventable ...