Although coronary artery lesions in treated animals were only modestly smaller than plaques in control animals, they had a significantly reduced inflammatory cell content and necrotic core area ...
Lipid-rich, noncalcified coronary plaques are considered more likely to rupture and are associated with a higher risk of potentially fatal ischemic cardiac events than fibrous or calcified lesions.
Plaque rupture and thrombosis frequently occurs at plaques that cause only modest coronary stenosis (< 50% luminal narrowing). STEMI most often results from coronary thrombosis after plaque ...
An individual may develop a rupture of an atheromatous plaque at any stage of the spectrum of coronary artery disease. The acute rupture of a plaque may lead to an acute myocardial infarction ...
Circulation. 2019;2b-d). Type 1 MI is “caused by atherothrombotic coronary artery disease and usually precipitated by atherosclerotic plaque disruption (rupture or erosion),” while a type 2 MI ...
Following publication of our studies, some physicians and patients question whether coronary atherosclerosis in athletes requires statins due to the potential lower non-calcified plaque burden and ...
The Edinburgh study is focused on improving detection of coronary atherothrombosis, a condition in which fatty deposits blocking the arteries - known as plaques - rupture without warning.