Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role in cutaneous autoimmune diseases, such as cutaneous lupus erythematosus (CLE ...
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Shared pathways between vascular calcification and bone growth offer new therapeutic avenue"The central signal transmitter for this is the cellular messenger cyclic guanosine monophosphate ... "If we know that several metabolic pathways in the vascular cells can lead to the production ...
Adenylyl cyclase creates multiple cyclic AMP molecules, which fan out and activate protein kinases (PKA, in this example). Protein kinases can enter the nucleus and affect transcription.
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