A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

of bacteriophage T4 DNA polymerase. Incubate the reaction mixture at 15–25 °C for 15 min. Set aside a small aliquot (3 μl) of the reaction for use in Step 11. 9| To the remainder of the ...

Figure 1: Sequence alignments, structures and expression patterns of mouse Dnmt3a and Dnmt3b.

Cell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics.

receive your kit and send back the required DNA samples. The last step is a short wait for your results to arrive digitally. A DNA test allows you to learn more about your heritage, health ...

Engineered enzymes play a crucial role in energy, materials, and medicine by enhancing natural functions or enabling new ...

While most of the steps mentioned above follow regular molecular cloning procedures, mutagenesis in the very first step is not trivial ... The pool of the long mutant oligos (up to 300 nt) can be used ...

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...

Understanding disease mechanisms and improving therapies The new study is an important step in this direction. The system of cross-membrane channels, created by DNA nanorobots, allows an efficient ...

The best disk cloning software is one of the easiest ways to make a backup, or 'clone', of your solid state or hard disk drives, allowing you to restore all your files in the event of a corruption ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.