Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Conversely, mid-infrared photoacoustic microscopy (MIR-PAM) allows for label-free imaging, preserving cell integrity. Yet, its reliance on longer wavelengths limits spatial resolution, making it ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Spindle assembly checkpoint (SAC) inhibitors are a recently developed class of drugs, which perturb chromosome segregation during cell division, induce chromosomal instability (CIN), and eventually ...

Accurately quantifying specific proteins from complex mixtures like cell lysates, for example ... with high sensitivity is achieved by using the Twin-Strep protein affinity tag and tritium-labeled 3H ...

Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself ... it's become possible to assay cell nuclei one at a time. This allows researchers to distinguish ...

Background: Acute lung injury (ALI) is a severe condition characterized by inflammation, tissue damage, and persistent activation of the cyclic GMP-AMP (cGAS)-stimulator of interferon genes (STING) ...