This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

Tempus AI, Inc. , a technology company leading the adoption of AI to advance precision medicine and patient care, today announced the national launch of the company's FDA-approved, NGS-based in vitro ...

EYLEA HD® and EYLEA® remained the U.S. anti-VEGF category leader in 2024; aggregate U.S. net product sales were $6 billion for full-year 2024, up 1% based on preliminary (unaudited) results EYLEA HD ...

Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell engagers (MATEs). MATEs consist of a CD3 binding domain to bind T cells and a ...

Accurately quantifying specific proteins from complex mixtures like cell lysates, for example ... with high sensitivity is achieved by using the Twin-Strep protein affinity tag and tritium-labeled 3H ...

Scientists are now uncovering that the basic mechanisms of memory also function in other types of cells. A kidney cell might not recall “Hotel California” as The Eagles sang it, but its learning ...

Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself ... it's become possible to assay cell nuclei one at a time. This allows researchers to distinguish ...

Department of Chemistry, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea ...

For molecular cloning, 2×MultiF Seamless Assembly Mix (RK21020) was from ABclonal, China, and Phanta Max Super-Fidelity DNA Polymerase (P505-d1 ... The identity of these cells was authenticated ...