Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

One is that the DNA template somehow becomes defective during replication, and causes the polymerase to pause (Figures 3 and 4a). For example, a DNA base can be chemically modified or ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

The double helix unwinds, and each strand serves as a template for the synthesis of a new complementary strand. DNA polymerase enzymes facilitate this process, ensuring accurate copying of the genetic ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Related: CRISPR Gene Editing May Cause Hundreds of Unintended Mutations in DNA Instead, the progress of the “lagging strand” polymerase looks a lot like stop and go traffic, stopping ...

Dr. Aaron Wenger tells us about SPRQ chemistry, highlighting its unique benefits and role in expanding our understanding of ...

A global team has made a significant advance in understanding how bacterial plasmids contribute to antibiotic resistance.