How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Pretzel Therapeutics Inc. has disclosed DNA polymerase subunit γ-1 (POLG) modulators reported to be useful for the treatment of neurodegeneration and mitochondrial diseases.

That discovery led to the invention of the polymerase chain reaction, or PCR (as in the PCR tests we took during the pandemic), which enables scientists to select specific DNA fragments and then ...

Biotechnology Co. Ltd. has described DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

This important study presents compelling observational data supporting a role for transcription and polysome accumulation in the separation of newly replicated bacterial chromosomes. The study is ...

Dr. Aaron Wenger tells us about SPRQ chemistry, highlighting its unique benefits and role in expanding our understanding of ...