1 Department of Rheumatology, University Medical Centre Nijmegen, The Netherlands 2 Department of Tumour Immunology laboratory, University Medical Centre Nijmegen, The Netherlands Correspondence to: ...

Ilixadencel consists of dendritic cells that have been activated with cytokines and toll-like-receptor ligands so they ‘act’ as if they have been infected by a virus. The cells are injected ...

Blander and Medzhitov explored the function of Toll-like receptor (TLR) signaling in controlling the maturation of phagosomes in macrophages and dendritic cells. As the phagosome is the key ...

Background Dendritic cells (DCs) have a pivotal role in the pathogenesis of systemic ... by flow cytometry for expression of subset-specific antigens (BDCA-2, CD11c, CD14, HLA-DR), ...

A group of proteins in our body, known as G protein-coupled receptors ... help dendritic cells sample the gut for foreign ...

Ig-like receptors ILT3 and ILT4 can be activated ... was utilized in the production of this manuscript. Phenotype of dendritic cells (DCs) may determine the type of immune reaction generated ...

Dendritic cells (DCs ... By contrast, foreign antigens result in DC maturation and DC-induced T-cell activation. Inappropriate maturation of DCs due to infections or tissue injury may cause ...

The bulky axillary LN metastases, which impaired activities in her normal daily routine, were dissected, and a vaccination regimen with autologous dendritic cells engineered with mRNA-encoded ...

Researchers at MedUni Vienna have developed a combination therapy using systemic interferon-I and topical imiquimod.

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.

development by activating the Aldh1a2/Raldh2 gene in dendritic cells through the aryl hydrocarbon receptor (AhR) and PU.1/IRF4 pathways. Raldh2, encoded by the Aldh1a2 gene, is expressed in ...