Interleukin-7 (IL-7) is produced by stromal cells, keratinocytes, and epithelial cells in host tissues or tumors and exerts a wide range of immune effects mediated by the IL-7 receptor (IL-7R). IL-7 ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

The revised work remains incomplete due to remaining concerns about experimental methodology, cell health, and lack of dendritic Na-spikes which have been recorded in previous works. Non-linear ...

an allogeneic bone marrow-derived mesenchymal stromal cell therapy, in pediatric patients with SR-aGvHD categorized as Grade B or D, excluding Grade B skin, assessed by the International Blood and ...

These structures resemble lymphoid follicles, typically featuring a core of B cells surrounded by T cells, along with dendritic cells, a supporting network of extracellular ... The TME in solid tumors ...

Lymphoid tissue inducer (LTi) cells, assigned to group 3 ILCs, interact with stromal cells and induce lymph node organogenesis ... although a particular subtype can potently promote inflammation in ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

At its third attempt, Mesoblast has secured FDA approval for Ryoncil as a treatment for children with graft-versus-host disease, the first-ever approval for a mesenchymal stromal cell (MSC ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...

Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...