It seeks to explain biological function in terms of molecular structure, dynamics and organization, from single molecules to supramolecular structures. Here, the authors use cryo electron ...

Deep generative models are rapidly becoming popular for the discovery of new molecules and materials. Such models learn on a large collection of molecular structures and produce novel compounds. In ...

Feb. 12, 2025 — Scientists have uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide spectrum ...

The new structure incorporates chemical groups called sulfonates to make it compatible with water, allowing it to function in real-world water systems, like rivers or wastewater. It uses a natural ...

The winning paper is titled “GABA A Receptor Subunit M2-M3 Linkers Have Asymmetric Roles in Pore Gating and Diazepam Modulation ... they serve as key molecular targets for widely prescribed ...

AI molecular design tool for de novo design, scaffold hopping, R-group replacement, linker design and molecule optimization.

The results of this experimentation are demonstrated in Figure 4. FT-IR is an invaluable tool for determining the chemical structure nature of the prepared samples, especially hydrogel samples. This ...

Hovenia dulcis is an herbal medicine promoting alcohol removal clearance, lipid-lowering, anti-inflammatory, and hepatoprotective properties. Hovenia dulcis has a variety of chemical components such ...

In this review, we highlight the evidence supporting the novel role of GABA with an emphasis on the molecular identity of the receptors expressed in these glial cells and the possible signaling ...

According to the above data, the selective agonists of the GABA-A receptor complex are the drugs of first choice in the drug treatment of insomnia. [22] Once treatment has started, monitoring and ...