Enzymes are crucial to life. They are nature's little catalysts. In the gut, they help us digest food. They can enhance ...

Engineered enzymes play a crucial role in energy, materials, and medicine by enhancing natural functions or enabling new ...

Manchester Institute of Biotechnology and Department of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.

A new ML-guided platform can design thousands of new enzymes, predict how they will behave in the real world, and test their ...

Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California 93106, United States Biomolecular Science and Engineering Program, University of California ...

In biotechnology, protein engineering is essential for developing new solutions across various fields. At Isomerase, we are leading this effort with tools like EvoSelect®, our protein computational ...

To overcome these hurdles, a team of researchers, led by Professor Anthony Green and Professor Igor Larrosa, have used directed evolution to develop a new enzyme capable of catalyzing S N Ar ...

By using automated directed evolution, the researchers were able to further engineer this enzyme to have the desired characteristics. The team evaluated more than 4,000 clones before identifying ...

The science of enzyme engineering is not new, only the application of machine learning to the field. Jewett and colleagues know it as “directed evolution.” They are shortcutting the process ...