Misregulation of protein–protein interactions (PPIs) underlies many diseases; hence, molecules that stabilize PPIs, known as molecular glues, are promising drug candidates. Identification of novel ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will ...

Verification of ASFV p30-cell protein interaction using GST-Pulldown assay. ASFV p30 bound to the recombinant Dab2 ... It also provides direction for the development of new vaccines or antiviral drugs ...

Ozempic (semaglutide) is a brand-name drug prescribed to treat certain conditions, such as type 2 diabetes. Ozempic has interactions with some other drugs, such as insulin, and certain supplements.

This study compares immune proteins and bioactive peptides in cow and camel milk, highlighting camel milk's lower allergenic ...

An interaction ... If you take certain drugs called strong CYP3A4 inhibitors: When you take a dose of Ubrelvy, certain enzymes break down the medication. (Enzymes are proteins that aid chemical ...

The assessment of causation for a potential drug interaction requires thoughtful ... concentration of the object drug (as measured by assay) after receiving the precipitant drug (eg, an enzyme ...

This principle is exploited in drug development: Drug molecules are designed to bind to specific proteins, altering their surface and, consequently, their behavior. The newly created "neo-surface" can ...