Hepatic fibrosis is a reversible wound healing response characterized by accumulation of extracellular matrix (ECM), or "scar," that follows chronic but not self-limited liver disease. The ECM ...

These platforms enable the generation of new, more relevant therapeutics against fibrosis and solid tumors, and meaningful biomarkers to ensure their delivery to the right patients. The ECM ...

New York, USA, Jan. 28, 2025 (GLOBE NEWSWIRE) -- Pulmonary Fibrosis Clinical Trial Pipeline Appears Robust With 110+ Key Pharma Companies Actively Working in the Therapeutics Segment | DelveInsight ...

Organoids contain multiple organ-specific cell types interacting with each other and ECM proteins, thereby mimicking the functionality ... such as inflammatory bowel disease using gastrointestinal ...

The results revealed that fibroblast-like cells predominantly drove fibrosis and scar formation in post-treatment tissue, gradually fanning out over the region where the tumor used to be and secreting ...

Lipid peroxidation products are emerging as important stimuli to ECM production ... efforts to use antioxidants as therapy for hepatic fibrosis (see section on Therapy of Hepatic Fibrosis ...