Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

This important study provides insights into the physiological role of RIPK1 in liver physiology, particularly during short-term fasting. The discovery that RIPK1 deficiency sensitizes the liver to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. TFs are key components of gene regulatory ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...