This fixed-dose tablet combines 600mg efavirenz, 200mg emtricitabine (FTC), and 245mg tenofovir disoproxil fumarate (TDF). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI), ...
Spanish researchers found that high plasma efavirenz levels correlated with CNS symptoms even after weeks or months of treatment. However, in a substudy of an ACTG trial, late neuropsychiatric ...
Baltimore County (UMBC), used a novel combination approach to increase understanding of the relevant mechanisms. First, tissue imaging showed that Efavirenz alters lipid metabolism in mouse brains.
Nevirapine and efavirenz are recommended as key drugs ... NNRTI-resistance mutations & their mechanism of drug resistance The most prevalent NNRTI-resistance mutations are K103N, Y181C and G190A.
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