Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of ...

For instance, studies on the ATP-binding cassette (ABC) transporter HrtBA in Corynebacterium diphtheriae have revealed how this efflux pump detoxifies excess heme by extracting it from the ...

Active efflux of drugs is a mechanism used by bacteria to resist drugs, and it is accomplished through the activation of efflux pumps, such as the MexAB-OprM efflux pump located in the mexR gene of ...

To combat these antibiotics, microorganisms have evolved multiple resistance mechanisms, including the direct inactivation or modification of antibiotics, protection of antibiotic targets, ...

Mahmood Ateyeh (’25, Western Hills High School) presented “Improving Photodeactivation Rate of Pathogens Using Nanoparticles and Efflux Pump Inhibitors” in physics and astronomy. Zahra Chasmawala (’25 ...

However, their utility has been severely limited due to the development of antimicrobial resistance through mechanisms such as efflux pumps and ribosomal protection. Currently, tetracyclines are ...

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In addition, we discuss emerging research implicating HSF1’s roles in autophagy, apoptosis, DNA damage repair, drug efflux, and thus chemoresistance. This article highlights the significance of HSF1 ...

A penis pump can help treat erectile dysfunction (ED) by using negative air pressure to increase blood flow in the penis and create an erection. Also known as a vacuum pump or vacuum erection device, ...

These MDR proteins lead to the production of drug efflux pumps, which actively transport taxanes and other drugs out of cancer cells. This prevents the accumulation of therapeutic intracellular ...

Experts say the antifungal resistance happens and spreads because of mutations at the drug's target site, preventing effective binding, increased production of efflux pumps that expel the drug ...

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